Nursing Care of Children, 4th Edition

Magisterial in its breadth of perspective and depth of research, The Great Influenza provides us with a precise and sobering model as we confront the epidemics looming on our own horizon. As Barry concludes, “The final lesson of 1918, a simple one yet one most difficult to execute, is that…those in authority must retain the public’s trust. The way to do that is to distort nothing, to put the best face on nothing, to try to manipulate no one. Lincoln said that first, and best. A leader must make whatever horror exists concrete. Only then will people be able to break it apart.”

At the height of World War I, history’s most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease.

Goodman & Gilman’s: The Pharmacological Basis of Therapeutics, Thirteenth Edition represents the pinnacle of authority and accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. Goodman & Gilman’s careful balance of basic science and clinical application has guided thousands of practitioners and students to a clear understanding of the drugs essential to preventing, diagnosing, and treating disease.

The Thirteenth Edition includes more than 500 color illustrations, with many new figures emphasizing mechanisms of drug action.  More than 30 new contributors have added to this edition, while the focus on basic principles is undiminished.

This edition is enhanced by timely new content:

• NEW chapters including Treatment of Pulmonary Arterial Hypertension, Immunity and Inflammation, Immunoglobulins and Vaccines, and Treatment of Viral Hepatitis
• Expanded coverage of cardiovascular disease, with separate chapters on  myocardial ischemia, hypertension, and heart failure 
• Increased emphasis on cellular signaling pathways involved in drug action
• Summary tables at the end of each chapter that organize drugs discussed in that chapter into relevant categories and detail therapeutic usage, clinical pharmacology, and tips
• Chapter Content Outlines at the beginning of each chapter
• Abbreviation boxes in every chapter to easily identify the abbreviations appearing in that chapter

This book covers in detail the mechanisms for how energy is managed in the human body. The basic principles that elucidate the reactivity and physical interactions of matter are addressed and quantified with simple approaches. Three-dimensional representations of molecules are presented throughout the book so molecules can be viewed as unique entities in their shape and function.

The book is focused on the molecular mechanisms of cellular processes in the context of human physiological situations such as fasting, feeding and physical exercise, in which metabolic regulation is highlighted. Furthermore the book uses key historical experiments that opened up new concepts in Biochemistry to further illustrate how the human body functions at molecular level, helping students to appreciate how scientific knowledge emerges.

This book also:

• Elucidates the foundations of the molecular events of life
  

Uses key historical experiments that opened up new concepts in Biochemistry to further illustrate how the human body functions at molecular level, helping students to appreciate how scientific knowledge emerges

• Provides realistic representations of molecules throughout the book
  

Advance Praise for Integrative Human Biochemistry

“This textbook provides a modern and integrative perspective of human biochemistry and will be a faithful companion to health science students following curricula in which this discipline is addressed. This textbook will be a most useful tool for the teaching community.”