Adams’s Outline of Fractures, 12th Edition

Magisterial in its breadth of perspective and depth of research, The Great Influenza provides us with a precise and sobering model as we confront the epidemics looming on our own horizon. As Barry concludes, “The final lesson of 1918, a simple one yet one most difficult to execute, is that…those in authority must retain the public’s trust. The way to do that is to distort nothing, to put the best face on nothing, to try to manipulate no one. Lincoln said that first, and best. A leader must make whatever horror exists concrete. Only then will people be able to break it apart.”

At the height of World War I, history’s most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease.

Goodman & Gilman’s: The Pharmacological Basis of Therapeutics, Thirteenth Edition represents the pinnacle of authority and accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. Goodman & Gilman’s careful balance of basic science and clinical application has guided thousands of practitioners and students to a clear understanding of the drugs essential to preventing, diagnosing, and treating disease.

The Thirteenth Edition includes more than 500 color illustrations, with many new figures emphasizing mechanisms of drug action.  More than 30 new contributors have added to this edition, while the focus on basic principles is undiminished.

This edition is enhanced by timely new content:

• NEW chapters including Treatment of Pulmonary Arterial Hypertension, Immunity and Inflammation, Immunoglobulins and Vaccines, and Treatment of Viral Hepatitis
• Expanded coverage of cardiovascular disease, with separate chapters on  myocardial ischemia, hypertension, and heart failure 
• Increased emphasis on cellular signaling pathways involved in drug action
• Summary tables at the end of each chapter that organize drugs discussed in that chapter into relevant categories and detail therapeutic usage, clinical pharmacology, and tips
• Chapter Content Outlines at the beginning of each chapter
• Abbreviation boxes in every chapter to easily identify the abbreviations appearing in that chapter

This state-of-the-art book reviews key issues and methods in medical image perception research through associated techniques, illustrations and examples. Written by key figures in the field, the book covers a range of topics including the history of medical image perception research, the basics of vision and cognition, and dedicated application areas, especially those concerned with the interface between the clinician and the display of medical image data. It summarizes many of the basic techniques used to conduct and analyze medical image perception and observer performance research, allowing readers to understand basic research techniques so they can adopt them for use in their own studies. Written for both newcomers to the field and experienced researchers, this book provides a broad overview of medical image perception, and will serve as a reference volume for years to come.