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Goodman & Gilman’s: The Pharmacological Basis of Therapeutics, Thirteenth Edition represents the pinnacle of authority and accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. Goodman & Gilman’s careful balance of basic science and clinical application has guided thousands of practitioners and students to a clear understanding of the drugs essential to preventing, diagnosing, and treating disease.

The Thirteenth Edition includes more than 500 color illustrations, with many new figures emphasizing mechanisms of drug action.  More than 30 new contributors have added to this edition, while the focus on basic principles is undiminished.

This edition is enhanced by timely new content:

• NEW chapters including Treatment of Pulmonary Arterial Hypertension, Immunity and Inflammation, Immunoglobulins and Vaccines, and Treatment of Viral Hepatitis
• Expanded coverage of cardiovascular disease, with separate chapters on  myocardial ischemia, hypertension, and heart failure 
• Increased emphasis on cellular signaling pathways involved in drug action
• Summary tables at the end of each chapter that organize drugs discussed in that chapter into relevant categories and detail therapeutic usage, clinical pharmacology, and tips
• Chapter Content Outlines at the beginning of each chapter
• Abbreviation boxes in every chapter to easily identify the abbreviations appearing in that chapter

This book covers in detail the mechanisms for how energy is managed in the human body. The basic principles that elucidate the reactivity and physical interactions of matter are addressed and quantified with simple approaches. Three-dimensional representations of molecules are presented throughout the book so molecules can be viewed as unique entities in their shape and function.

The book is focused on the molecular mechanisms of cellular processes in the context of human physiological situations such as fasting, feeding and physical exercise, in which metabolic regulation is highlighted. Furthermore the book uses key historical experiments that opened up new concepts in Biochemistry to further illustrate how the human body functions at molecular level, helping students to appreciate how scientific knowledge emerges.

This book also:

• Elucidates the foundations of the molecular events of life
  

Uses key historical experiments that opened up new concepts in Biochemistry to further illustrate how the human body functions at molecular level, helping students to appreciate how scientific knowledge emerges

• Provides realistic representations of molecules throughout the book
  

Advance Praise for Integrative Human Biochemistry

“This textbook provides a modern and integrative perspective of human biochemistry and will be a faithful companion to health science students following curricula in which this discipline is addressed. This textbook will be a most useful tool for the teaching community.”

Titles in the Pocket Tutor series give practical guidance on subjects that medical students and foundation doctors need help with “on the go”, at a highly affordable price that puts them within reach of those rotating through modular courses or working on attachment.

• Common investigations (ECG, imaging, etc)
• Clinical skills (patient examination, etc.)
• Clinical specialties that students perceive as too small to merit a textbook (psychiatry, renal medicine)

Key points

• Practical, accessible introduction to a subject that students find daunting, but which juniors will encounter as part of orthopaedic and emergency rotations
• Logical, sequential content: relevant basic science; then chapters devoted to the clinical essentials of orthopaedics and the disorders and injuries seen most commonly in practice
• Descriptions of common disorders are enhanced by Clinical Scenarios (Patient presents with…), which help students and trainees to recognise and manage common presenting problems